All Phenotypes Fnip1<tm1.1Baba> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fnip1^tm1.1Baba
targeted mutation 1.1, Masaya Baba
MGI:5445115

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Tg(Ckmm-cre)5Khn/0	involves: C57BL/6 * FVB	MGI:5897113
cn2	Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Tg(Cdh16-cre)91Igr/0	involves: C57BL/6 * ICR	MGI:5897110
cn3	Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Fnip2^tm1.1Lss/Fnip2^tm1.1Lss Tg(Cdh16-cre)91Igr/0	involves: C57BL/6 * ICR	MGI:5897114
cn4	Flcn^tm1Baba/Flcn^tm1Baba Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Fnip2^tm1.1Lss/Fnip2^tm1.1Lss Tg(Cdh16-cre)91Igr/0	involves: C57BL/6 * ICR	MGI:5897115

Allelic Composition	Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Tg(Ckmm-cre)5Khn/0
Genetic Background	involves: C57BL/6 * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fnip1^tm1.1Baba mutation (0 available); any Fnip1 mutation (60 available)
Tg(Ckmm-cre)5Khn mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

abnormal muscle morphology ( J:220672 )

• red colored

abnormal muscle physiology ( J:220672 )

• increased mitochondrial biogenesis in muscle

cardiovascular system

cardiac hypertrophy ( J:220672 )

cellular

abnormal mitochondrial physiology ( J:220672 )

• increased mitochondrial biogenesis in muscle

growth/size/body

cardiac hypertrophy ( J:220672 )

Allelic Composition	Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Tg(Cdh16-cre)91Igr/0
Genetic Background	involves: C57BL/6 * ICR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fnip1^tm1.1Baba mutation (0 available); any Fnip1 mutation (60 available)
Tg(Cdh16-cre)91Igr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

kidney cyst ( J:220672 )

• occasional tiny cysts

growth/size/body

kidney cyst ( J:220672 )

• occasional tiny cysts

Allelic Composition	Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Fnip2^tm1.1Lss/Fnip2^tm1.1Lss Tg(Cdh16-cre)91Igr/0
Genetic Background	involves: C57BL/6 * ICR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fnip1^tm1.1Baba mutation (0 available); any Fnip1 mutation (60 available)
Fnip2^tm1.1Lss mutation (0 available); any Fnip2 mutation (60 available)
Tg(Cdh16-cre)91Igr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:220672 )

• survival time is about 3 weeks

renal/urinary system

polycystic kidney ( J:220672 )

enlarged kidney ( J:220672 )

cellular

abnormal mitochondrial physiology ( J:220672 )

• increased respiratory capacity and mitochondrial surface area indicating increased mitochondrial biogenesis

growth/size/body

polycystic kidney ( J:220672 )

enlarged kidney ( J:220672 )

Allelic Composition	Flcn^tm1Baba/Flcn^tm1Baba Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Fnip2^tm1.1Lss/Fnip2^tm1.1Lss Tg(Cdh16-cre)91Igr/0
Genetic Background	involves: C57BL/6 * ICR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flcn^tm1Baba mutation (0 available); any Flcn mutation (40 available)
Fnip1^tm1.1Baba mutation (0 available); any Fnip1 mutation (60 available)
Fnip2^tm1.1Lss mutation (0 available); any Fnip2 mutation (60 available)
Tg(Cdh16-cre)91Igr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

polycystic kidney ( J:220672 )

• no increase in severity of cystic phenotype compared to mutant mice wild-type for Flcn

enlarged kidney ( J:220672 )

• no increase in severity of phenotype compared to mutant mice wild-type for Flcn

growth/size/body

polycystic kidney ( J:220672 )

• no increase in severity of cystic phenotype compared to mutant mice wild-type for Flcn

enlarged kidney ( J:220672 )

• no increase in severity of phenotype compared to mutant mice wild-type for Flcn

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/02/2024 MGI 6.24