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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdx2tm1.1Aral
targeted mutation 1.1, Amy Ralston
MGI:5445743
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cdx2tm1.1Aral/Cdx2tm1.1Aral
Tg(Zp3-cre)93Knw/0 		involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL MGI:5445746
cn2
 		Cdx2tm1.1Aral/Cdx2tm1.2Aral
Tg(Zp3-cre)93Knw/0 		involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL MGI:5445747
cn3
 		Cdx2tm1.1Aral/Cdx2tm1Fbe
Tg(Zp3-cre)93Knw/0 		involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL MGI:5445751


Genotype
MGI:5445746
cn1
Allelic
Composition		 Cdx2tm1.1Aral/Cdx2tm1.1Aral
Tg(Zp3-cre)93Knw/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx2tm1.1Aral mutation (0 available); any Cdx2 mutation (22 available)
Tg(Zp3-cre)93Knw mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:189005 )
N
• when bred to wild-type males females produce viable offspring indicating maternal expression is not required for development




Genotype
MGI:5445747
cn2
Allelic
Composition		 Cdx2tm1.1Aral/Cdx2tm1.2Aral
Tg(Zp3-cre)93Knw/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx2tm1.1Aral mutation (0 available); any Cdx2 mutation (22 available)
Cdx2tm1.2Aral mutation (0 available); any Cdx2 mutation (22 available)
Tg(Zp3-cre)93Knw mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:189005 )
N
• when bred to wild-type males females produce viable offspring indicating maternal expression is not required for development




Genotype
MGI:5445751
cn3
Allelic
Composition		 Cdx2tm1.1Aral/Cdx2tm1Fbe
Tg(Zp3-cre)93Knw/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx2tm1.1Aral mutation (0 available); any Cdx2 mutation (22 available)
Cdx2tm1Fbe mutation (0 available); any Cdx2 mutation (22 available)
Tg(Zp3-cre)93Knw mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:189005 )
• reach the blastocyst stage then collapse around implantation

embryo
embryonic growth arrest ( J:189005 )
• reach the blastocyst stage then collapse around implantation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory