About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdx2tm1.1Aral
targeted mutation 1.1, Amy Ralston
MGI:5445743
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cdx2tm1.1Aral/Cdx2tm1.1Aral
Tg(Zp3-cre)93Knw/0 		involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL MGI:5445746
cn2
 		Cdx2tm1.1Aral/Cdx2tm1.2Aral
Tg(Zp3-cre)93Knw/0 		involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL MGI:5445747
cn3
 		Cdx2tm1.1Aral/Cdx2tm1Fbe
Tg(Zp3-cre)93Knw/0 		involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL MGI:5445751


Genotype
MGI:5445746
cn1
Allelic
Composition		 Cdx2tm1.1Aral/Cdx2tm1.1Aral
Tg(Zp3-cre)93Knw/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx2tm1.1Aral mutation (0 available); any Cdx2 mutation (22 available)
Tg(Zp3-cre)93Knw mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:189005 )
N
• when bred to wild-type males females produce viable offspring indicating maternal expression is not required for development




Genotype
MGI:5445747
cn2
Allelic
Composition		 Cdx2tm1.1Aral/Cdx2tm1.2Aral
Tg(Zp3-cre)93Knw/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx2tm1.1Aral mutation (0 available); any Cdx2 mutation (22 available)
Cdx2tm1.2Aral mutation (0 available); any Cdx2 mutation (22 available)
Tg(Zp3-cre)93Knw mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:189005 )
N
• when bred to wild-type males females produce viable offspring indicating maternal expression is not required for development




Genotype
MGI:5445751
cn3
Allelic
Composition		 Cdx2tm1.1Aral/Cdx2tm1Fbe
Tg(Zp3-cre)93Knw/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdx2tm1.1Aral mutation (0 available); any Cdx2 mutation (22 available)
Cdx2tm1Fbe mutation (0 available); any Cdx2 mutation (22 available)
Tg(Zp3-cre)93Knw mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:189005 )
• reach the blastocyst stage then collapse around implantation

embryo
embryonic growth arrest ( J:189005 )
• reach the blastocyst stage then collapse around implantation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory