Phenotypes associated with this allele

• Allele Symbol: Cdc20^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5445785
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cdc20^tm1.1(KOMP)Vlcg/Cdc20^tm1.1(KOMP)Vlcg	B6N(Cg)-Cdc20^tm1.1(KOMP)Vlcg/J	MGI:5630947
ht2	Cdc20^tm1.1(KOMP)Vlcg/Cdc20^+	B6N(Cg)-Cdc20^tm1.1(KOMP)Vlcg/J	MGI:5630946

Genotype
MGI:5630947

hm1

• Allelic Composition: Cdc20^{tm1.1(KOMP)Vlcg}/Cdc20^{tm1.1(KOMP)Vlcg}
• Genetic Background: B6N(Cg)-Cdc20^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 11674A-C9

Data Sources

IMPC Data for Cdc20

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5630946

ht2

• Allelic Composition: Cdc20^{tm1.1(KOMP)Vlcg}/Cdc20⁺
• Genetic Background: B6N(Cg)-Cdc20^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 11674A-C9

Data Sources

IMPC Data for Cdc20

behavior/neurological

increased grip strength ( J:211773 )

♀

IMPC - JAX

cardiovascular system

increased heart weight ( J:211773 )

♂

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - JAX

increased circulating glucose level ( J:211773 )

♀

IMPC - JAX

increased fasting circulating glucose level ( J:211773 )

♂

IMPC - JAX

improved glucose tolerance ( J:211773 )

♂

IMPC - JAX