Phenotypes associated with this allele

• Allele Symbol: Ghrhr^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5445807
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ghrhr^tm1.1(KOMP)Vlcg/Ghrhr^tm1.1(KOMP)Vlcg	C57BL/6N-Ghrhr^tm1.1(KOMP)Vlcg/J	MGI:5608241
ht2	Ghrhr^tm1.1(KOMP)Vlcg/Ghrhr^+	C57BL/6N-Ghrhr^tm1.1(KOMP)Vlcg/J	MGI:5631166

Genotype
MGI:5608241

hm1

• Allelic Composition: Ghrhr^{tm1.1(KOMP)Vlcg}/Ghrhr^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Ghrhr^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 10030C-F5

Data Sources

IMPC Data for Ghrhr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - JAX

behavior/neurological

increased grip strength ( J:211773 )

IMPC - JAX

decreased vertical activity ( J:211773 )

IMPC - JAX

hyperactivity ( J:211773 )

IMPC - JAX

abnormal sleep behavior ( J:211773 )

♀

IMPC - JAX

cardiovascular system

decreased heart weight ( J:211773 )

IMPC - JAX

growth/size/body

decreased lean body mass ( J:211773 )

IMPC - JAX

decreased body length ( J:211773 )

IMPC - JAX

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - JAX

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - JAX

thrombocytopenia ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - JAX

increased circulating triglyceride level ( J:211773 )

♂

IMPC - JAX

skeleton

abnormal bone structure ( J:211773 )

♀

IMPC - JAX

decreased bone mineral content ( J:211773 )

IMPC - JAX

decreased bone mineral density ( J:211773 )

IMPC - JAX

Genotype
MGI:5631166

ht2

• Allelic Composition: Ghrhr^{tm1.1(KOMP)Vlcg}/Ghrhr⁺
• Genetic Background: C57BL/6N-Ghrhr^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 10030C-F5

Data Sources

IMPC Data for Ghrhr

behavior/neurological

hyperactivity ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

♂

IMPC - JAX

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - JAX