Phenotypes associated with this allele

• Allele Symbol: Nsf^{tm1b(KOMP)Mbp}
• Allele Name: targeted mutation 1b, Mouse Biology Program, UC Davis
• Allele ID: MGI:5446014
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nsf^tm1b(KOMP)Mbp/Nsf^tm1b(KOMP)Mbp	C57BL/6N-Nsf^tm1b(KOMP)Mbp/J	MGI:5631354
ht2	Nsf^tm1b(KOMP)Mbp/Nsf^+	C57BL/6N-Nsf^tm1b(KOMP)Mbp/J	MGI:5631353

Genotype
MGI:5631354

hm1

• Allelic Composition: Nsf^{tm1b(KOMP)Mbp}/Nsf^{tm1b(KOMP)Mbp}
• Genetic Background: C57BL/6N-Nsf^{tm1b(KOMP)Mbp}/J
• Cell Lines: DEPD00520_2_A09

Data Sources

IMPC Data for Nsf

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5631353

ht2

• Allelic Composition: Nsf^{tm1b(KOMP)Mbp}/Nsf⁺
• Genetic Background: C57BL/6N-Nsf^{tm1b(KOMP)Mbp}/J
• Cell Lines: DEPD00520_2_A09

Data Sources

IMPC Data for Nsf

behavior/neurological

decreased thigmotaxis ( J:211773 )

IMPC - JAX

hematopoietic system

increased hemoglobin content ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - JAX

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - JAX

vision/eye

abnormal retina morphology ( J:211773 )

♂

IMPC - JAX