About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zfhx3tm1.1Jtd
targeted mutation 1.1, Jin-Tang Dong
MGI:5446504
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zfhx3tm1.1Jtd/Zfhx3tm1.1Jtd involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL MGI:5446520
cn2
 		Zfhx3tm1.1Jtd/Zfhx3+ involves: 129S6/SvEvTac MGI:5661033
cn3
 		Zfhx3tm1.1Jtd/Zfhx3tm1.1Jtd
Tg(Pbsn-cre)4Prb/0 		involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL MGI:5446522
cn4
 		Zfhx3tm1.1Jtd/Zfhx3+
Tg(EIIa-cre)C5379Lmgd/0 		involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL MGI:5446521


Genotype
MGI:5446520
hm1
Allelic
Composition		 Zfhx3tm1.1Jtd/Zfhx3tm1.1Jtd
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfhx3tm1.1Jtd mutation (1 available); any Zfhx3 mutation (130 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:189563 )
• mice are viable and fertile with no gross abnormalities




Genotype
MGI:5661033
cn2
Allelic
Composition		 Zfhx3tm1.1Jtd/Zfhx3+
Genetic
Background		 involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfhx3tm1.1Jtd mutation (1 available); any Zfhx3 mutation (130 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
prolonged circadian behavior period ( J:223990 )
• mice transduced with a virus expressing cre recombinase exhibit an approximate 1.5-hour circadian period lengthening in the suprachiasmatic nucleus




Genotype
MGI:5446522
cn3
Allelic
Composition		 Zfhx3tm1.1Jtd/Zfhx3tm1.1Jtd
Tg(Pbsn-cre)4Prb/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Pbsn-cre)4Prb mutation (2 available)
Zfhx3tm1.1Jtd mutation (1 available); any Zfhx3 mutation (130 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
increased prostate intraepithelial neoplasia incidence ( J:189563 )
• in mice with cre-expression in the prostate

neoplasm
increased prostate intraepithelial neoplasia incidence ( J:189563 )
• in mice with cre-expression in the prostate

reproductive system
increased prostate intraepithelial neoplasia incidence ( J:189563 )
• in mice with cre-expression in the prostate




Genotype
MGI:5446521
cn4
Allelic
Composition		 Zfhx3tm1.1Jtd/Zfhx3+
Tg(EIIa-cre)C5379Lmgd/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(EIIa-cre)C5379Lmgd mutation (4 available)
Zfhx3tm1.1Jtd mutation (1 available); any Zfhx3 mutation (130 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:189563 )
• half of mice die by weaning




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory