About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hspb2tm1.1Ijb
targeted mutation 1.1, Ivor J Benjamin
MGI:5447475
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hspb2tm1.1Ijb/Hspb2tm1.1Ijb involves: 129S4/SvJaeSor * FVB MGI:5447480


Genotype
MGI:5447480
hm1
Allelic
Composition		 Hspb2tm1.1Ijb/Hspb2tm1.1Ijb
Genetic
Background		 involves: 129S4/SvJaeSor * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hspb2tm1.1Ijb mutation (0 available); any Hspb2 mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cellular respiration ( J:189659 )
• following transverse aortic constriction, mice exhibit reduced state 3 mitochondrial respiration and ATP production compared with controls
abnormal mitochondrial physiology ( J:189659 )
• following transverse aortic constriction, mice exhibit reduced state 3 mitochondrial respiration and ATP production compared with controls

cardiovascular system
cardiovascular system phenotype ( J:189659 )
N
• mice exhibit normal cardiac hypertrophic response to pressure overload




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory