endocrine/exocrine glands
• when cre-expressing adenovirus is introduced under the bursa, 72% of ovaries exhibit cytologic abnormalities in the ovarian surface epithelium
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• 27% of mice injected with cre-expressing adenovirus under the bursa develop minimal to mild atypical hyperplasia with occasional papillary epithelial projections 3 to 24 months postinduction
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• mice injected with cre-expressing adenovirus under the bursa develop ovarian surface epithelium proliferation with progression only to stage I of ovarian cancer
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• 27% of mice injected with cre-expressing adenovirus under the bursa develop ovarian surface epithelium carcinoma in situ with no invasion into the underlying ovary or overlying bursa
• 18% of mice injected with cre-expressing adenovirus under the bursa exhibit ovarian tumors that progress to serous epithelial ovarian cancer pathology with early invasion into ovary and bursa
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reproductive system
• when cre-expressing adenovirus is introduced under the bursa, 72% of ovaries exhibit cytologic abnormalities in the ovarian surface epithelium
|
• 27% of mice injected with cre-expressing adenovirus under the bursa develop minimal to mild atypical hyperplasia with occasional papillary epithelial projections 3 to 24 months postinduction
|
• mice injected with cre-expressing adenovirus under the bursa develop ovarian surface epithelium proliferation with progression only to stage I of ovarian cancer
|
• 27% of mice injected with cre-expressing adenovirus under the bursa develop ovarian surface epithelium carcinoma in situ with no invasion into the underlying ovary or overlying bursa
• 18% of mice injected with cre-expressing adenovirus under the bursa exhibit ovarian tumors that progress to serous epithelial ovarian cancer pathology with early invasion into ovary and bursa
|
neoplasm
• mice injected with cre-expressing adenovirus under the bursa develop ovarian surface epithelium proliferation with progression only to stage I of ovarian cancer
|
• 27% of mice injected with cre-expressing adenovirus under the bursa develop ovarian surface epithelium carcinoma in situ with no invasion into the underlying ovary or overlying bursa
• 18% of mice injected with cre-expressing adenovirus under the bursa exhibit ovarian tumors that progress to serous epithelial ovarian cancer pathology with early invasion into ovary and bursa
|
growth/size/body
• 27% of mice injected with cre-expressing adenovirus under the bursa develop minimal to mild atypical hyperplasia with occasional papillary epithelial projections 3 to 24 months postinduction
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