All Phenotypes Zfp281<tm1.1Jlwa> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Zfp281^tm1.1Jlwa
targeted mutation 1.1, Jianlong Wang
MGI:5449148

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zfp281^tm1.1Jlwa/Zfp281^tm1.1Jlwa	involves: 129S1/Sv	MGI:5449149

Allelic Composition	Zfp281^tm1.1Jlwa/Zfp281^tm1.1Jlwa
Genetic Background	involves: 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfp281^tm1.1Jlwa mutation (0 available); any Zfp281 mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:190201 )

• mice die between E7.5 and E8.5

cellular

abnormal cell differentiation ( J:190201 )

• embryonic stem (ES) cells exhibit abnormal embryoid body differentiation compared with wild-type cells

• however, ES cells exhibit normal survival and proliferation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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