All Phenotypes Abcg1<tm1Tall> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Abcg1^tm1Tall
targeted mutation 1, Alan Tall
MGI:5450880

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Abca1^tm1Jp/Abca1^tm1Jp Abcg1^tm1Tall/Abcg1^tm1Tall Lyz2^tm1(cre)Ifo/Lyz2⁺	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6	MGI:5451017
cn2	Abca1^tm1Jp/Abca1^tm1Jp Abcg1^tm1Tall/Abcg1^tm1Tall Tg(Itgax-cre,-EGFP)4097Ach/0	involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J	MGI:5451018

Allelic Composition	Abca1^tm1Jp/Abca1^tm1Jp Abcg1^tm1Tall/Abcg1^tm1Tall Lyz2^tm1(cre)Ifo/Lyz2⁺
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abca1^tm1Jp mutation (2 available); any Abca1 mutation (90 available)
Abcg1^tm1Tall mutation (1 available); any Abcg1 mutation (46 available)
Lyz2^tm1(cre)Ifo mutation (14 available); any Lyz2 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal bone marrow cell morphology/development ( J:190966 )

• mice exhibit an increase in colony-forming units in the blood

immune system

increased interleukin-17 secretion ( J:190966 )

increased interleukin-23 secretion ( J:190966 )

• 1.5-fold in the spleen

Allelic Composition	Abca1^tm1Jp/Abca1^tm1Jp Abcg1^tm1Tall/Abcg1^tm1Tall Tg(Itgax-cre,-EGFP)4097Ach/0
Genetic Background	involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J