Analysis Tools|
Allele Symbol Allele Name Allele ID |
Del(13Simc1-B4galt7)2Dja deletion, Chr 13, David J Adams 2 MGI:5451135 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Dilation of the renal pelvicalyceal system in Del(13Simc1-B4galt7)2Dja/+ mice
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• at 28 weeks
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• at 28 weeks
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• at 28 weeks
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• at E15.5
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• at E15.5
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| N |
• mice exhibit normal kidney function and do not develop kidney stones
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• at 10, 28 and 52 weeks in all mice
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• mice exhibit reduced ability to distinguish familiar stimulus mouse after 24 h and spend more time investigating the familiar mouse compared with wild-type mice
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| N |
• unlike patients with Sotos Syndrome 1, mice do not exhibit skeletal or craniofacial defects
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| N |
• unlike patients with Sotos Syndrome 1, mice do not exhibit skeletal or craniofacial defects
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| Sotos syndrome | DOID:14748 |
OMIM:PS117550 |
J:190741 | |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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