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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ano1tm1.1Jwo
targeted mutation 1.1, John N Wood
MGI:5461852
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ano1tm1.1Jwo/Ano1tm1.1Jwo
Aviltm2(cre)Fawa/Avil+ 		involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL MGI:5461903


Genotype
MGI:5461903
cn1
Allelic
Composition		 Ano1tm1.1Jwo/Ano1tm1.1Jwo
Aviltm2(cre)Fawa/Avil+
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ano1tm1.1Jwo mutation (0 available); any Ano1 mutation (60 available)
Aviltm2(cre)Fawa mutation (2 available); any Avil mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:191353 )
N
• mice exhibit normal balance, motor coordination, locomotion and mechanical sensitivities
increased thermal nociceptive threshold ( J:191353 )
• in response to tail immersion in hot water or radiant heat

nervous system
abnormal sensory neuron morphology ( J:191353 )
• dorsal root ganglion sensory neurons exhibit reduced heat-evoked inward chloride current compared with control neurons

integument
integument phenotype ( J:191353 )
N
• mice exhibit normal mechanical sensitivities




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory