Phenotypes associated with this allele

• Allele Symbol: Larp7^tm1Ymat
• Allele Name: targeted mutation 1, Yasuhisa Matsui
• Allele ID: MGI:5463352
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Larp7^tm1Ymat/Larp7^tm1Ymat	involves: 129P2/OlaHsd * C57BL/6	MGI:5463354

Genotype
MGI:5463354

hm1

• Allelic Composition: Larp7^tm1Ymat/Larp7^tm1Ymat
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, incomplete penetrance ( J:191206 )

• all die between E17.5 and birth

perinatal lethality, complete penetrance ( J:191206 )

• all die between E17.5 and birth

reproductive system

decreased primordial germ cell number ( J:191206 )

• in both males and females at E13.5 but not at E10.5

decreased primordial germ cell proliferation ( J:191206 )

• decrease in proliferation at E12.5

growth/size/body

decreased fetal size ( J:191206 )

• slightly smaller at E16.5

nervous system

open neural tube ( J:191206 )

• Background Sensitivity: in some embryos with a higher contribution of 129 genetic background but not in embryos derived from later backcrosses to C57BL/6

embryo

open neural tube ( J:191206 )

• Background Sensitivity: in some embryos with a higher contribution of 129 genetic background but not in embryos derived from later backcrosses to C57BL/6

cellular

decreased primordial germ cell number ( J:191206 )

• in both males and females at E13.5 but not at E10.5

decreased primordial germ cell proliferation ( J:191206 )

• decrease in proliferation at E12.5