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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Serpinb7-icre)1Fech
transgene insertion 1, Feng Chen
MGI:5464108
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Adam10tm2Psa/Adam10tm2Psa
Tg(Serpinb7-icre)1Fech/0 		involves: 129P2/OlaHsd * C57BL/6 * CBA MGI:5474059


Genotype
MGI:5474059
cn1
Allelic
Composition		 Adam10tm2Psa/Adam10tm2Psa
Tg(Serpinb7-icre)1Fech/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adam10tm2Psa mutation (1 available); any Adam10 mutation (38 available)
Tg(Serpinb7-icre)1Fech mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
digestive/alimentary phenotype ( J:191899 )
N
• mice do not show overt abnormalities, even though cre expression is detected in esophagus and the stomach; no differences in histology are detected in esophagus and glandular hindstomach relative to controls
• mice grow at similar rate to littermates, as shown by body weight measurements
forestomach hypoplasia ( J:191899 )
• forestomach hypoplasia is detected with decreased depth of gastric pits in adult mice
• no digestive problems are observed




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory