reproductive system
• numerous invaginations of the ovarian surface epithelium formed tube-like structures in the ovarian cortex, and multiple nests of StAR- positive cells resembling lutein cells were present throughout the ovary of sterile female mice
• tubulostromal hyperplasia in sterile female mice
• however, fertile female mice exhibit normal ovaries
|
• in sterile mice
• however, fertile female mice exhibit normal follicle numbers
|
small ovary
(
J:192479
)
• very small in sterile female mice
• however, fertile female mice exhibit normal ovary weight
|
• stromal fibrosis in sterile female mice
• however, fertile female mice exhibit normal uteri
|
• some uterine glands in sterile female mice exhibit an ectopic layer of cells immediately beneath the columnar epithelial layer unlike in wild-type mice
|
• in sterile females
|
• some female mice fail to produce offspring
|
• female mice produce small litters compared with wild-type mice
• however, the number of litters is normal
|
• from some female mice
|
endocrine/exocrine glands
• some uterine glands in sterile female mice exhibit an ectopic layer of cells immediately beneath the columnar epithelial layer unlike in wild-type mice
|
• in sterile females
|
• numerous invaginations of the ovarian surface epithelium formed tube-like structures in the ovarian cortex, and multiple nests of StAR- positive cells resembling lutein cells were present throughout the ovary of sterile female mice
• tubulostromal hyperplasia in sterile female mice
• however, fertile female mice exhibit normal ovaries
|
• in sterile mice
• however, fertile female mice exhibit normal follicle numbers
|
small ovary
(
J:192479
)
• very small in sterile female mice
• however, fertile female mice exhibit normal ovary weight
|