Phenotypes associated with this allele

• Allele Symbol: Zfp568^tm1Ckjs
• Allele Name: targeted mutation 1, C K James Shen
• Allele ID: MGI:5466413
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Tg(Nes-cre)1Kln/0 Zfp568^tm1Ckjs/Zfp568^tm1Ckjs	involves: C57BL/6J * SJL	MGI:5466414

Genotype
MGI:5466414

cn1

• Allelic Composition: Tg(Nes-cre)1Kln/0; Zfp568^tm1Ckjs/Zfp568^tm1Ckjs
• Genetic Background: involves: C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:192224 )

N • mice exhibit normal cortical layering and neuronal migration

abnormal neuronal precursor proliferation ( J:192224 )

• reduced average size of primary and secondary neurospheres grown from neural stem cells due to reduced proliferation

• reduced proliferation in subventricular zone but not in the dentate gyrus

decreased brain weight ( J:192224 )

• at birth but not in adult mice

behavior/neurological

behavior/neurological phenotype ( J:192224 )

N • mice exhibit normal performance in a Morris water maze

increased aggression ( J:192224 )

pup cannibalization ( J:192224 )

♀

cellular

abnormal neuronal precursor proliferation ( J:192224 )

• reduced average size of primary and secondary neurospheres grown from neural stem cells due to reduced proliferation

• reduced proliferation in subventricular zone but not in the dentate gyrus