Phenotypes associated with this allele

• Allele Symbol: Rbm4b^tm1Wtarn
• Allele Name: targeted mutation 1, Woan-Yuh Tarn
• Allele ID: MGI:5467988
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rbm4b^tm1Wtarn/Rbm4b^tm1Wtarn	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:5467990

Genotype
MGI:5467990

hm1

• Allelic Composition: Rbm4b^tm1Wtarn/Rbm4b^tm1Wtarn
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

small pancreatic islets ( J:192831 )

• moderately reduced in size

homeostasis/metabolism

hyperglycemia ( J:192831 )

♂ • in males after an 8 hour fast

impaired glucose tolerance ( J:192831 )

♂ • fasting males have an inefficient insulin response to glucose challenge

♂ • in fasting males blood glucose levels are higher than those of the controls after glucose feeding