cellular
• very few spermatocytes in tubules at age 3 weeks
• most tubules devoid of spermatocytes at age 4 weeks
• very few mature sperm in tubules at age 8 weeks
• fewer meiotic cells in 20-day old testes
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endocrine/exocrine glands
• many tubules show extensive vacuolization between age 3 and 8 weeks
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growth/size/body
• 10-15% lower body weight up to age 2 months
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reproductive system
• very few spermatocytes in tubules at age 3 weeks
• most tubules devoid of spermatocytes at age 4 weeks
• very few mature sperm in tubules at age 8 weeks
• fewer meiotic cells in 20-day old testes
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• many tubules show extensive vacuolization between age 3 and 8 weeks
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• 3 out of 8 mice did not produce offspring
• reduced average number of litters sired
• reduced average litter size
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