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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Vangl2M1Yzcm
mutation 1, Yangzhou University Comparative Medicine Center
MGI:5468724
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Vangl2M1Yzcm/Vangl2+ C57BL/6J-Vangl2M1Yzcm MGI:5468814
ht2
 		Vangl2M1Yzcm/Vangl2+ either: C57BL/6J-Vangl2m1Yzcm or (involves: C3H/HeJ * C57BL/6J) MGI:5468816
ht3
 		Vangl2M1Yzcm/Vangl2+ involves: C3H/HeJ * C57BL/6J MGI:5468815


Genotype
MGI:5468814
ht1
Allelic
Composition		 Vangl2M1Yzcm/Vangl2+
Genetic
Background		 C57BL/6J-Vangl2M1Yzcm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vangl2M1Yzcm mutation (0 available); any Vangl2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:5468816
ht2
Allelic
Composition		 Vangl2M1Yzcm/Vangl2+
Genetic
Background		 either: C57BL/6J-Vangl2m1Yzcm or (involves: C3H/HeJ * C57BL/6J)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vangl2M1Yzcm mutation (0 available); any Vangl2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neural tube morphology ( J:193593 )
• in 4 of 16 mice at between E12.5 and E18.5
abnormal embryonic neuroepithelium morphology ( J:193593 )
• exposed neuroepithelium at E12.5
enlarged floor plate ( J:193593 )
• enlarged at E12.5
open neural tube ( J:193593 )
• from the midbrain to tail in some mice

growth/size/body
decreased fetal size ( J:193593 )
• in some mice at E18.5
fetal growth retardation ( J:193593 )
• in some mice at E18.5

vision/eye
failure of eyelid fusion ( J:193593 )
• in some mice

embryo
abnormal neural tube morphology ( J:193593 )
• in 4 of 16 mice at between E12.5 and E18.5
abnormal embryonic neuroepithelium morphology ( J:193593 )
• exposed neuroepithelium at E12.5
enlarged floor plate ( J:193593 )
• enlarged at E12.5
open neural tube ( J:193593 )
• from the midbrain to tail in some mice




Genotype
MGI:5468815
ht3
Allelic
Composition		 Vangl2M1Yzcm/Vangl2+
Genetic
Background		 involves: C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vangl2M1Yzcm mutation (0 available); any Vangl2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail

skeleton
skeleton phenotype ( J:193593 )
N
• skeletons are normal




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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory