Analysis Tools|
Allele Symbol Allele Name Allele ID |
Igs4tm1Hsas targeted mutation 1, Hiroyuki Sasaki MGI:5469286 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• although no homozygous mice are identified this may indicate a problem with genotyping since the J1 ES cells used to generate mice contains a duplication in this area and the ratio of heterozygotes to wild-type mice is twice as much as expected from crosses involving heterozygous parents
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• reporter expression is recovered following cre-mediated removal of the neo sequence from the Watson piwiRNA generating locus on chromosome 17
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• the reporter is post-transcriptionally repressed after the time of pachytene piRNA generation
• however, no change in reporter locus methylation is detected
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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