All Phenotypes Vps52<t-w5> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vps52^t-w5
t, wild 5
MGI:5469352

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	t^w5/t^w5 Vps52^t-w5/Vps52^t-w5	B6.Cg-t^w5	MGI:5464109
cx2	Vps52^tm1.2Kab/t^w5 Vps52^t-w5	involves: C57BL * C57BL/6 * CBA/JNCrlj * DBA	MGI:5464110

Allelic Composition	t^w5/t^w5 Vps52^t-w5/Vps52^t-w5
Genetic Background	B6.Cg-t^w5

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t^w5 mutation (3 available); any t mutation (19 available)
Vps52^t-w5 mutation (0 available); any Vps52 mutation (42 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal ectoderm development ( J:190873 )

• the epithelial layer of the embryonic ectoderm fails to form by E6.5

• cell proliferation is very low in the embryonic ectoderm

• however, formation of extraembryonic tissues is similar to controls

decreased embryo size ( J:190873 )

• at E6.5

abnormal blastocyst morphology ( J:190873 )

• absence of cavitation in embryonic tissues; however, cavitation is seen in extraembryonic tissues

growth/size/body

decreased embryo size ( J:190873 )

• at E6.5

Allelic Composition	Vps52^tm1.2Kab/t^w5 Vps52^t-w5
Genetic Background	involves: C57BL * C57BL/6 * CBA/JNCrlj * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t^w5 mutation (3 available); any t mutation (19 available)
Vps52^tm1.2Kab mutation (1 available); any Vps52 mutation (42 available)
Vps52^t-w5 mutation (0 available); any Vps52 mutation (42 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal ectoderm development ( J:190873 )

• at E6.5 all embryos show embryonic ectoderm defects typical of mice homozygous for t^w5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24