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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Polg2tm1.1Wcc
targeted mutation 1.1, William C Copeland
MGI:5470227
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Polg2tm1.1Wcc/Polg2tm1.1Wcc involves: C57BL/6 * CBA MGI:5470233


Genotype
MGI:5470233
hm1
Allelic
Composition
Polg2tm1.1Wcc/Polg2tm1.1Wcc
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polg2tm1.1Wcc mutation (0 available); any Polg2 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cellular
• increase in fatty droplet with swollen and disorganized cristae
• swollen and disorganized cristae
• complete lack of COX1(mt-Co1) activity

embryo





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory