Phenotypes associated with this allele

• Allele Symbol: Atr^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5471285
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atr^tm1b(KOMP)Wtsi/Atr^tm1b(KOMP)Wtsi	B6N(Cg)-Atr^tm1b(KOMP)Wtsi/2J	MGI:5630887
ht2	Atr^tm1b(KOMP)Wtsi/Atr^+	B6N(Cg)-Atr^tm1b(KOMP)Wtsi/2J	MGI:5630886

Genotype
MGI:5630887

hm1

• Allelic Composition: Atr^{tm1b(KOMP)Wtsi}/Atr^{tm1b(KOMP)Wtsi}
• Genetic Background: B6N(Cg)-Atr^{tm1b(KOMP)Wtsi}/2J
• Cell Lines: EPD0755_1_H02

Data Sources

IMPC Data for Atr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5630886

ht2

• Allelic Composition: Atr^{tm1b(KOMP)Wtsi}/Atr⁺
• Genetic Background: B6N(Cg)-Atr^{tm1b(KOMP)Wtsi}/2J
• Cell Lines: EPD0755_1_H02

Data Sources

IMPC Data for Atr

cardiovascular system

increased heart weight ( J:211773 )

♂

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♀

IMPC - JAX

decreased circulating glucose level ( J:211773 )

♂

IMPC - JAX

nervous system

abnormal spinal cord morphology ( J:211773 )

♀

IMPC - JAX