Phenotypes associated with this allele

• Allele Symbol: Asf1a^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5471306
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Asf1a^tm1b(KOMP)Wtsi/Asf1a^tm1b(KOMP)Wtsi	B6N(Cg)-Asf1a^tm1b(KOMP)Wtsi/2J	MGI:5630871
ht2	Asf1a^tm1b(KOMP)Wtsi/Asf1a^+	B6N(Cg)-Asf1a^tm1b(KOMP)Wtsi/2J	MGI:5759105

Genotype
MGI:5630871

hm1

• Allelic Composition: Asf1a^{tm1b(KOMP)Wtsi}/Asf1a^{tm1b(KOMP)Wtsi}
• Genetic Background: B6N(Cg)-Asf1a^{tm1b(KOMP)Wtsi}/2J
• Cell Lines: EPD0754_3_D01

Data Sources

IMPC Data for Asf1a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

abnormal neural tube morphology ( J:211773 )

♂

IMPC - JAX

abnormal neural tube closure ( J:211773 )

♂

IMPC - JAX

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

nervous system

abnormal neural tube morphology ( J:211773 )

♂

IMPC - JAX

abnormal neural tube closure ( J:211773 )

♂

IMPC - JAX

Genotype
MGI:5759105

ht2

• Allelic Composition: Asf1a^{tm1b(KOMP)Wtsi}/Asf1a⁺
• Genetic Background: B6N(Cg)-Asf1a^{tm1b(KOMP)Wtsi}/2J
• Cell Lines: EPD0754_3_D01

Data Sources

IMPC Data for Asf1a

behavior/neurological

decreased thigmotaxis ( J:211773 )

♀

IMPC - JAX

embryo

abnormal embryo turning ( J:211773 )

IMPC - JAX

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

homeostasis/metabolism

increased circulating insulin level ( J:211773 )

IMPC - JAX

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - JAX