Phenotypes associated with this allele

• Allele Symbol: Foxo3^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5471395
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Foxo3^tm1.1(KOMP)Vlcg/Foxo3^tm1.1(KOMP)Vlcg	C57BL/6N-Foxo3^tm1.1(KOMP)Vlcg/J	MGI:5631138

Genotype
MGI:5631138

hm1

• Allelic Composition: Foxo3^{tm1.1(KOMP)Vlcg}/Foxo3^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Foxo3^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 13508A-C5

Data Sources

IMPC Data for Foxo3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased startle reflex ( J:211773 )

IMPC - JAX

decreased locomotor activity ( J:211773 )

♂

IMPC - JAX

abnormal sleep behavior ( J:211773 )

♀

IMPC - JAX

cardiovascular system

increased heart weight ( J:211773 )

♀

IMPC - JAX

prolonged QRS complex duration ( J:211773 )

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

♀

IMPC - JAX

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - JAX

increased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - JAX

increased mean corpuscular volume ( J:211773 )

♂

IMPC - JAX

thrombocytopenia ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♂

IMPC - JAX

decreased circulating chloride level ( J:211773 )

♀

IMPC - JAX

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - JAX

skeleton

decreased bone mineral density ( J:211773 )

♂

IMPC - JAX

vision/eye

sclerocornea ( J:211773 )

♂

IMPC - JAX

abnormal retina morphology ( J:211773 )

IMPC - JAX