Phenotypes associated with this allele

• Allele Symbol: Guca1a^tm1Itl
• Allele Name: targeted mutation 1, inGenious Targeting Laboratory
• Allele ID: MGI:5473300
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Guca1a^tm1Itl/Guca1a^tm1Itl	involves: 129S6/SvEvTac * C57BL/6NTac	MGI:5473303

Genotype
MGI:5473303

hm1

• Allelic Composition: Guca1a^tm1Itl/Guca1a^tm1Itl
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina morphology ( J:192199 )

• altered calcium ion sensitivity

abnormal photoreceptor outer segment morphology ( J:192199 )

• slightly larger length and repeat disk distance

abnormal rod electrophysiology ( J:192199 )

• the shape of the response to dimmer flashes is altered with increased single-photon response amplitude and time-to-peak and faster recovery than in wild-type mice

nervous system

abnormal photoreceptor outer segment morphology ( J:192199 )

• slightly larger length and repeat disk distance