Phenotypes associated with this allele

• Allele Symbol: Zzef1^{tm2.1(KOMP)Vlcg}
• Allele Name: targeted mutation 2.1, Velocigene
• Allele ID: MGI:5474781
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zzef1^tm2.1(KOMP)Vlcg/Zzef1^tm2.1(KOMP)Vlcg	B6N(Cg)-Zzef1^tm2.1(KOMP)Vlcg/J	MGI:5763859
hm2	Zzef1^tm2.1(KOMP)Vlcg/Zzef1^tm2.1(KOMP)Vlcg	C57BL/6N-Zzef1^tm2.1(KOMP)Vlcg/Ucd	MGI:6480648

Genotype
MGI:5763859

hm1

• Allelic Composition: Zzef1^{tm2.1(KOMP)Vlcg}/Zzef1^{tm2.1(KOMP)Vlcg}
• Genetic Background: B6N(Cg)-Zzef1^{tm2.1(KOMP)Vlcg}/J
• Cell Lines: 18561B-G9

Data Sources

IMPC Data for Zzef1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased coping response ( J:211773 )

♂

IMPC - JAX

hyperactivity ( J:211773 )

♂

IMPC - JAX

abnormal sleep behavior ( J:211773 )

IMPC - JAX

craniofacial

absent teeth ( J:211773 )

♂

IMPC - JAX

growth/size/body

absent teeth ( J:211773 )

♂

IMPC - JAX

decreased body length ( J:211773 )

♀

IMPC - JAX

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

IMPC - JAX

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - JAX

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - JAX

decreased circulating calcium level ( J:211773 )

IMPC - JAX

increased circulating potassium level ( J:211773 )

♂

IMPC - JAX

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - JAX

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - JAX

integument

abnormal coat/hair pigmentation ( J:211773 )

♀

IMPC - JAX

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

♀

IMPC - JAX

skeleton

absent teeth ( J:211773 )

♂

IMPC - JAX

Genotype
MGI:6480648

hm2

• Allelic Composition: Zzef1^{tm2.1(KOMP)Vlcg}/Zzef1^{tm2.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Zzef1^{tm2.1(KOMP)Vlcg}/Ucd
• Cell Lines: 18561A-A10

Data Sources

IMPC Data for Zzef1

growth/size/body

increased kidney weight ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

increased kidney weight ( J:211773 )

♂

IMPC - UCD