Analysis Tools
immune system
| N |
• normal thymus development
• normal lymphoid tissue development
• re-stimulation response of CD8+ T cells is comparable to controls
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• half as many CD8+ cells at 8 days after LCMV infection as in controls
• most CD8+ cells are "naive" rather than activated
• two fold drop in CD8+ cells secreting IFNgamma, TNFalpha, or IL-2 at 6 and 8 days
• number of cells secreting cytokines is higher at 12 days
• IL-7R positive effector cells are largely absent
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|
• two fold drop in CD8+ cells secreating IFNgamma, TNFalpha, or IL-2 at 6 and 8 days
• number of cells secreting cytokines is higher at 12 days
|
|
• less CD8+ T cell expansion in response to lymphocytic choriomeningitis virus (LCMV) infection than in controls after 8 days
• half as many CD8+ cells at 8 days after infection as in controls
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hematopoietic system
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• half as many CD8+ cells at 8 days after LCMV infection as in controls
• most CD8+ cells are "naive" rather than activated
• two fold drop in CD8+ cells secreting IFNgamma, TNFalpha, or IL-2 at 6 and 8 days
• number of cells secreting cytokines is higher at 12 days
• IL-7R positive effector cells are largely absent
|
|
• two fold drop in CD8+ cells secreating IFNgamma, TNFalpha, or IL-2 at 6 and 8 days
• number of cells secreting cytokines is higher at 12 days
|
