Analysis Tools
immune system
| N |
• CD8+ numbers and CD8+/CD4+ ratio recovered from condition in mice lacking Tg(H2-K-BCL2)1Josd
|
|
Allele Symbol Allele Name Allele ID |
Il7rtm2Iku targeted mutation 2, Koichi Ikuta MGI:5475476 |
||||||||||||
| Summary |
2 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• CD8+ numbers and CD8+/CD4+ ratio recovered from condition in mice lacking Tg(H2-K-BCL2)1Josd
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• increased B cell lineages
|
|
• slightly
• number of double negative thymocytes is doubled
|
|
• generation of mature CD4+ cells is impaired
• 2-3 fold reduction of proliferation in the thymus
|
|
• generation of mature CD4+ cells is impaired
• 2-3 fold reduction of proliferation in the thymus
|
|
• reduced frequency of stage 3 invariant NKT cells
• double negative invariant NKT cells are reduced
|
|
• increased in the thymus by 1.5 fold
|
|
• increased B cell lineages
|
|
• slightly
• number of double negative thymocytes is doubled
|
|
• generation of mature CD4+ cells is impaired
• 2-3 fold reduction of proliferation in the thymus
|
|
• generation of mature CD4+ cells is impaired
• 2-3 fold reduction of proliferation in the thymus
|
|
• reduced frequency of stage 3 invariant NKT cells
• double negative invariant NKT cells are reduced
|
|
• increased in the thymus by 1.5 fold
|
|
• slightly
• number of double negative thymocytes is doubled
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 06/12/2024 MGI 6.13 |
|
|
|
||