About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rhbgtm1.1Idw
targeted mutation 1, I David Weiner
MGI:5477809
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Rhbgtm1.1Idw/Rhbgtm1.1Idw
Tg(ATP6V1B1-cre)45Rnel/0 		involves: C57BL/6 MGI:5477810


Genotype
MGI:5477810
cn1
Allelic
Composition		 Rhbgtm1.1Idw/Rhbgtm1.1Idw
Tg(ATP6V1B1-cre)45Rnel/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbgtm1.1Idw mutation (1 available); any Rhbg mutation (22 available)
Tg(ATP6V1B1-cre)45Rnel mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:195261 )
N
• no differences in titratable acid excretion, urine pH, urinary electrolyte excretion, serum bicarbonate levels, or serum potassium levels are detected under basal or acid loading conditions
decreased urine ammonia level ( J:195261 )
• following acid loading, urinary ammonia levels are reduced by about 25% compared to controls
• however, basal ammonia excretion is similar to controls

renal/urinary system
decreased urine ammonia level ( J:195261 )
• following acid loading, urinary ammonia levels are reduced by about 25% compared to controls
• however, basal ammonia excretion is similar to controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory