Phenotypes associated with this allele

• Allele Symbol: Pcna^tm1.1Scwh
• Allele Name: targeted mutation 1.1, Shao-Chun Wang
• Allele ID: MGI:5478543
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pcna^tm1.1Scwh/Pcna^tm1.1Scwh	involves: FVB	MGI:5478547

Genotype
MGI:5478547

hm1

• Allelic Composition: Pcna^tm1.1Scwh/Pcna^tm1.1Scwh
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

abnormal adipose tissue development ( J:193874 )

• following adipogenic induction, mouse embryonic fibroblasts fail to re-enter cell cycle or differentiate into mature adipocytes unlike wild-type cells

decreased white fat cell number ( J:193874 )

• in peri-ovarian fat pads of mice fed a high fat diet

decreased percent body fat/body weight ( J:193874 )

• when fed a high fat diet

growth/size/body

increased lean body mass ( J:193874 )

• when fed a high fat diet

decreased body weight ( J:193874 )

• slightly when fed standard chow

• when fed a high fat diet

decreased susceptibility to weight gain ( J:193874 )

• when fed a high fat diet