About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adgre1m2Btlr
mutation 2, Bruce Beutler
MGI:5478734
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adgre1m2Btlr/Adgre1m2Btlr C57BL/6J-Adgre1m2Btlr MGI:5478739


Genotype
MGI:5478739
hm1
Allelic
Composition		 Adgre1m2Btlr/Adgre1m2Btlr
Genetic
Background		 C57BL/6J-Adgre1m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adgre1m2Btlr mutation (1 available); any Adgre1 mutation (79 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased macrophage cell number ( J:195410 )
• loss of F4/80+ macrophages in the peripheral blood
abnormal macrophage physiology ( J:195410 )
• loss of F4/80+ macrophages in the peripheral blood

hematopoietic system
decreased macrophage cell number ( J:195410 )
• loss of F4/80+ macrophages in the peripheral blood
abnormal macrophage physiology ( J:195410 )
• loss of F4/80+ macrophages in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory