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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hltftm1.1Arte
targeted mutation 1.1, TaconicArtemis
MGI:5484565
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hltftm1.1Arte/Hltftm1.1Arte Not Specified MGI:5484566


Genotype
MGI:5484566
hm1
Allelic
Composition		 Hltftm1.1Arte/Hltftm1.1Arte
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hltftm1.1Arte mutation (0 available); any Hltf mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuron physiology ( J:193813 )
• absence of the the fluoxetine-induced increase in survival of newborn neurons that is seen in wild-type controls
abnormal neuronal precursor proliferation ( J:193813 )
• absence of the fluoxetine-induced increase in neuronal precursor proliferation that is seen in wild-type controls

behavior/neurological
impaired behavioral response to xenobiotic ( J:193813 )
• fail to show a decrease in latency to feed in response to fluoxetine treatment in a novelty suppressed feeding assay, unlike wild-type controls

cellular
abnormal neuronal precursor proliferation ( J:193813 )
• absence of the fluoxetine-induced increase in neuronal precursor proliferation that is seen in wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory