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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Edartm1.1Bamo
targeted mutation 1.1, Bruce A Morgan
MGI:5484581
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Edartm1.1Bamo/Edartm1.1Bamo involves: 129S4/SvJae * FVB MGI:5484582
ht2
Edartm1.1Bamo/Edar+ involves: 129S4/SvJae * FVB MGI:5484583
ht3
Edardl-J/Edartm1.1Bamo involves: 129S4/SvJae * C3HeB/FeJ * FVB/N MGI:5484585


Genotype
MGI:5484582
hm1
Allelic
Composition
Edartm1.1Bamo/Edartm1.1Bamo
Genetic
Background
involves: 129S4/SvJae * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edartm1.1Bamo mutation (0 available); any Edar mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• increase in branch density in pre-estrus mice
• increase in the number of glands per footpad
• increase in the proportion of thick hairs
• increase in the number of the thickest, four-cell awl hairs and a decrease in the number of three-cell hairs

endocrine/exocrine glands
N
• Meibomian gland and sebaceous gland sizes appear similar to wild-type controls
• increase in branch density in pre-estrus mice
• increase in the number of glands per footpad

adipose tissue

limbs/digits/tail
• increase in the number of glands per footpad




Genotype
MGI:5484583
ht2
Allelic
Composition
Edartm1.1Bamo/Edar+
Genetic
Background
involves: 129S4/SvJae * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edartm1.1Bamo mutation (0 available); any Edar mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• increase in the number of glands per footpad compared to wild-type mice but fewer than in homozygous mutants

integument
• increase in the number of glands per footpad compared to wild-type mice but fewer than in homozygous mutants

limbs/digits/tail
• increase in the number of glands per footpad compared to wild-type mice but fewer than in homozygous mutants




Genotype
MGI:5484585
ht3
Allelic
Composition
Edardl-J/Edartm1.1Bamo
Genetic
Background
involves: 129S4/SvJae * C3HeB/FeJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edardl-J mutation (2 available); any Edar mutation (30 available)
Edartm1.1Bamo mutation (0 available); any Edar mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• increase in the number of glands per foot pads compared to mice heterozygous for Edardl-J alone

integument
• increase in the number of glands per foot pads compared to mice heterozygous for Edardl-J alone

limbs/digits/tail
• increase in the number of glands per foot pads compared to mice heterozygous for Edardl-J alone





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory