All Phenotypes Edar<tm1.1Bamo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Edar^tm1.1Bamo
targeted mutation 1.1, Bruce A Morgan
MGI:5484581

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Edar^tm1.1Bamo/Edar^tm1.1Bamo	involves: 129S4/SvJae * FVB	MGI:5484582
ht2	Edar^tm1.1Bamo/Edar⁺	involves: 129S4/SvJae * FVB	MGI:5484583
ht3	Edar^dl-J/Edar^tm1.1Bamo	involves: 129S4/SvJae * C3HeB/FeJ * FVB/N	MGI:5484585

Allelic Composition	Edar^tm1.1Bamo/Edar^tm1.1Bamo
Genetic Background	involves: 129S4/SvJae * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edar^tm1.1Bamo mutation (0 available); any Edar mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal branching of the mammary ductal tree ( J:193816 )

• increase in branch density in pre-estrus mice

increased eccrine gland number ( J:193816 )

• increase in the number of glands per footpad

abnormal auchene hair morphology ( J:193816 )

• increase in the proportion of thick hairs

abnormal awl hair morphology ( J:193816 )

• increase in the number of the thickest, four-cell awl hairs and a decrease in the number of three-cell hairs

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:193816 )

N	• Meibomian gland and sebaceous gland sizes appear similar to wild-type controls

abnormal branching of the mammary ductal tree ( J:193816 )

• increase in branch density in pre-estrus mice

increased eccrine gland number ( J:193816 )

• increase in the number of glands per footpad

adipose tissue

abnormal mammary fat pad morphology ( J:193816 )

• smaller in area

limbs/digits/tail

increased eccrine gland number ( J:193816 )

• increase in the number of glands per footpad

Allelic Composition	Edar^tm1.1Bamo/Edar⁺
Genetic Background	involves: 129S4/SvJae * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edar^tm1.1Bamo mutation (0 available); any Edar mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

increased eccrine gland number ( J:193816 )

• increase in the number of glands per footpad compared to wild-type mice but fewer than in homozygous mutants

integument

increased eccrine gland number ( J:193816 )

• increase in the number of glands per footpad compared to wild-type mice but fewer than in homozygous mutants

limbs/digits/tail

increased eccrine gland number ( J:193816 )

• increase in the number of glands per footpad compared to wild-type mice but fewer than in homozygous mutants

Allelic Composition	Edar^dl-J/Edar^tm1.1Bamo
Genetic Background	involves: 129S4/SvJae * C3HeB/FeJ * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edar^dl-J mutation (2 available); any Edar mutation (30 available)
Edar^tm1.1Bamo mutation (0 available); any Edar mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

increased eccrine gland number ( J:193816 )

• increase in the number of glands per foot pads compared to mice heterozygous for Edar^dl-J alone

integument

increased eccrine gland number ( J:193816 )

• increase in the number of glands per foot pads compared to mice heterozygous for Edar^dl-J alone

limbs/digits/tail

increased eccrine gland number ( J:193816 )

• increase in the number of glands per foot pads compared to mice heterozygous for Edar^dl-J alone

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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