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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nox1tm1.1Anrt
targeted mutation 1.1, Asma Nusrat
MGI:5486319
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Nox1tm1.1Anrt/Nox1tm1.1Anrt
Tg(Vil1-cre)997Gum/0 		involves: C57BL/6J * SJL MGI:5486337


Genotype
MGI:5486337
cn1
Allelic
Composition		 Nox1tm1.1Anrt/Nox1tm1.1Anrt
Tg(Vil1-cre)997Gum/0
Genetic
Background		 involves: C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nox1tm1.1Anrt mutation (0 available); any Nox1 mutation (12 available)
Tg(Vil1-cre)997Gum mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal wound healing ( J:194294 )
• in a wounded healing assay, colonic epithelial cells treated with Ac2-26 do not exhibit an increase in reactive oxygen species generation unlike wild-type cells
• wound healing is not enhanced by treatment with ANXA1 unlike wounded wild-type colonic epithelium

immune system
colitis ( J:194294 )
• DSS-induced colitis is not improved by ANXA1 treatment unlike in wild-type mice

cellular
abnormal redox activity ( J:194294 )
• in a wounded healing assay, colonic epithelial cells treated with Ac2-26 do not exhibit an increase in reactive oxygen species generation unlike wild-type cells

digestive/alimentary system
colitis ( J:194294 )
• DSS-induced colitis is not improved by ANXA1 treatment unlike in wild-type mice




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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory