Phenotypes associated with this allele

• Allele Symbol: Ube2a^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5488492
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ube2a^tm1.1(KOMP)Vlcg/Ube2a^tm1.1(KOMP)Vlcg	C57BL/6N-Ube2a^tm1.1(KOMP)Vlcg/J	MGI:6263808
ot2	Ube2a^tm1.1(KOMP)Vlcg/Y	C57BL/6N-Ube2a^tm1.1(KOMP)Vlcg/J	MGI:6263807

Genotype
MGI:6263808

hm1

• Allelic Composition: Ube2a^{tm1.1(KOMP)Vlcg}/Ube2a^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Ube2a^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 12204A-C12

Data Sources

IMPC Data for Ube2a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased startle reflex ( J:211773 )

♀

IMPC - JAX

decreased grip strength ( J:211773 )

♀

IMPC - JAX

decreased locomotor activity ( J:211773 )

♀

IMPC - JAX

cardiovascular system

increased heart weight ( J:211773 )

♀

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

decreased circulating serum albumin level ( J:211773 )

♀

IMPC - JAX

reproductive system

female infertility ( J:211773 )

♀

IMPC - JAX

Genotype
MGI:6263807

ot2

• Allelic Composition: Ube2a^{tm1.1(KOMP)Vlcg}/Y
• Genetic Background: C57BL/6N-Ube2a^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 12204A-C12

Data Sources

IMPC Data for Ube2a

behavior/neurological

hyperactivity ( J:211773 )

♂

IMPC - JAX

cardiovascular system

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - JAX

vision/eye

abnormal retina blood vessel morphology ( J:211773 )

♂

IMPC - JAX