Phenotypes associated with this allele

• Allele Symbol: Slc6a3^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5488785
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc6a3^tm1b(KOMP)Wtsi/Slc6a3^tm1b(KOMP)Wtsi	C57BL/6N-Slc6a3^tm1b(KOMP)Wtsi/J	MGI:5631556
ht2	Slc6a3^tm1b(KOMP)Wtsi/Slc6a3^+	C57BL/6N-Slc6a3^tm1b(KOMP)Wtsi/J	MGI:5757732

Genotype
MGI:5631556

hm1

• Allelic Composition: Slc6a3^{tm1b(KOMP)Wtsi}/Slc6a3^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Slc6a3^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0304_3_G01

Data Sources

IMPC Data for Slc6a3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal tooth morphology ( J:211773 )

♂

IMPC - JAX

absent teeth ( J:211773 )

♂

IMPC - JAX

growth/size/body

abnormal tooth morphology ( J:211773 )

♂

IMPC - JAX

absent teeth ( J:211773 )

♂

IMPC - JAX

skeleton

abnormal tooth morphology ( J:211773 )

♂

IMPC - JAX

absent teeth ( J:211773 )

♂

IMPC - JAX

Genotype
MGI:5757732

ht2

• Allelic Composition: Slc6a3^{tm1b(KOMP)Wtsi}/Slc6a3⁺
• Genetic Background: C57BL/6N-Slc6a3^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0304_3_G01

Data Sources

IMPC Data for Slc6a3

behavior/neurological

hyperactivity ( J:211773 )

IMPC - JAX

cardiovascular system

increased heart weight ( J:211773 )

♂

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

decreased circulating free fatty acids level ( J:211773 )

♂

IMPC - JAX

increased circulating sodium level ( J:211773 )

IMPC - JAX