Phenotypes associated with this allele

• Allele Symbol: Kif14^tm1Tskk
• Allele Name: targeted mutation 1, Toshiaki Sakisaka
• Allele ID: MGI:5488956
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kif14^tm1Tskk/Kif14^tm1Tskk	C57BL/6N-Kif14^tm1Tskk	MGI:5488959

Genotype
MGI:5488959

hm1

• Allelic Composition: Kif14^tm1Tskk/Kif14^tm1Tskk
• Genetic Background: C57BL/6N-Kif14^tm1Tskk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

flat head ( J:195809 )

nervous system

decreased brain size ( J:195809 )

abnormal hippocampus morphology ( J:195809 )

• disrupted cytoarchitecture

abnormal cerebral cortex morphology ( J:195809 )

• disrupted cytoarchitecture

abnormal cerebellar cortex morphology ( J:195809 )

• disrupted cytoarchitecture

optic nerve hypoplasia ( J:195809 )

• slender nerve

abnormal spinal cord morphology ( J:195809 )

• transparent indicating lack of myelination

demyelination ( J:195809 )

• in the central nervous system

behavior/neurological

ataxia ( J:195809 )

• at P10, worsening with time

impaired balance ( J:195809 )

• at P12, mice cannot stand on a platform compared with wild-type mice

abnormal gait ( J:195809 )

• wide and uncoordinated with frequent falls

craniofacial

flat head ( J:195809 )

vision/eye

optic nerve hypoplasia ( J:195809 )

• slender nerve