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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Or8a1tm38Mom
targeted mutation 38, Peter Mombaerts
MGI:5489815
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Or8a1tm38Mom/Or8a1tm38Mom B6;129P2-Or8a1tm38Mom/MomJ MGI:5788649


Genotype
MGI:5788649
hm1
Allelic
Composition		 Or8a1tm38Mom/Or8a1tm38Mom
Genetic
Background		 B6;129P2-Or8a1tm38Mom/MomJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or8a1tm38Mom mutation (1 available); any Or8a1 mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
taste/olfaction
decreased olfactory sensory neuron number ( J:233447 )
• the number of olfactory sensory neurons expresssing this allele rapidly decreases as assessed between postnatal day 10 and 96

craniofacial
decreased olfactory sensory neuron number ( J:233447 )
• the number of olfactory sensory neurons expresssing this allele rapidly decreases as assessed between postnatal day 10 and 96

nervous system
decreased olfactory sensory neuron number ( J:233447 )
• the number of olfactory sensory neurons expresssing this allele rapidly decreases as assessed between postnatal day 10 and 96
abnormal olfactory bulb interneuron morphology ( J:233447 )
• axons of olfactory sensory neurons that express this allele show poor outgrowth and most do not reach the cribiform plate or dorsal bulb

growth/size/body
abnormal olfactory sensory neuron morphology ( J:233447 )
abnormal olfactory receptor morphology ( J:233447 )
decreased olfactory sensory neuron number ( J:233447 )
• the number of olfactory sensory neurons expresssing this allele rapidly decreases as assessed between postnatal day 10 and 96

respiratory system
decreased olfactory sensory neuron number ( J:233447 )
• the number of olfactory sensory neurons expresssing this allele rapidly decreases as assessed between postnatal day 10 and 96




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory