All Phenotypes Sum2<M1Jus> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sum2^M1Jus
mutation 1, Monica J Justice
MGI:5489913

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Mecp2^tm1.1Bird/Y Sum2^M1Jus/Sum2⁺	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J	MGI:5499846

Allelic Composition	Mecp2^tm1.1Bird/Y Sum2^M1Jus/Sum2⁺
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2^tm1.1Bird mutation (1 available); any Mecp2 mutation (41 available)
Sum2^M1Jus mutation (0 available); any Sum2 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

extended life span ( J:198551 )

• lifespan in increased at least 3 weeks from the average 50% lethality time point of Mecp2^tm1.1Bird hemizygotes

behavior/neurological

lethargy ( J:198551 )

• at 20 weeks but ameliorated compared to in Mecp2^tm1.1Bird hemizygotes

limb grasping ( J:198551 )

• at 8 and 20 weeks but ameliorated compared to in Mecp2^tm1.1Bird hemizygotes

tremors ( J:198551 )

• at 8 and 20 weeks but ameliorated compared to in Mecp2^tm1.1Bird hemizygotes

immune system

eye inflammation ( J:198551 )

• unlike Mecp2^tm1.1Bird hemizygotes

dermatitis ( J:198551 )

• unlike Mecp2^tm1.1Bird hemizygotes

growth/size/body

abnormal body weight ( J:198551 )

• at 20 weeks but ameliorated compared to in Mecp2^tm1.1Bird hemizygotes

vision/eye

eye inflammation ( J:198551 )

• unlike Mecp2^tm1.1Bird hemizygotes

integument

dermatitis ( J:198551 )

• unlike Mecp2^tm1.1Bird hemizygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24