Phenotypes associated with this allele

• Allele Symbol: T^{tm1(cre/ERT2)Hssk}
• Allele Name: targeted mutation 1, Hiroshi Sasaki
• Allele ID: MGI:5490031
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	T^tm1(cre/ERT2)Hssk/T^tm1(cre/ERT2)Hssk	involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR	MGI:5490041
ht2	T^tm1(cre/ERT2)Hssk/T^+	involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR	MGI:5490042

Genotype
MGI:5490041

hm1

• Allelic Composition: T^{tm1(cre/ERT2)Hssk}/T^{tm1(cre/ERT2)Hssk}
• Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:194054 )

• no viable homozygotes are obtained

Genotype
MGI:5490042

ht2

• Allelic Composition: T^{tm1(cre/ERT2)Hssk}/T⁺
• Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR

limbs/digits/tail

abnormal tail morphology ( J:194054 )

• mice show varying degrees of tail defects similar heterozygous brachyury (T) mutants

short tail ( J:194054 )

• observed in some heterozygotes

absent tail ( J:194054 )

• observed in some heterozygotes

curly tail ( J:194054 )

• observed in some heterozygotes