Phenotypes associated with this allele

• Allele Symbol: Bloc1s2^{tm1.1(KOMP)Mbp}
• Allele Name: targeted mutation 1.1, Mouse Biology Program, UC Davis
• Allele ID: MGI:5490495
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bloc1s2^tm1.1(KOMP)Mbp/Bloc1s2^tm1.1(KOMP)Mbp	B6N(Cg)-Bloc1s2^tm1.1(KOMP)Mbp/J	MGI:5630907
ht2	Bloc1s2^tm1.1(KOMP)Mbp/Bloc1s2^+	B6N(Cg)-Bloc1s2^tm1.1(KOMP)Mbp/J	MGI:5630906

Genotype
MGI:5630907

hm1

• Allelic Composition: Bloc1s2^{tm1.1(KOMP)Mbp}/Bloc1s2^{tm1.1(KOMP)Mbp}
• Genetic Background: B6N(Cg)-Bloc1s2^{tm1.1(KOMP)Mbp}/J
• Cell Lines: DEPD00501_4_C09

Data Sources

IMPC Data for Bloc1s2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal pericardium morphology ( J:211773 )

♂

IMPC - JAX

hemorrhage ( J:211773 )

IMPC - JAX

craniofacial

abnormal craniofacial morphology ( J:211773 )

♂

IMPC - JAX

embryo

abnormal limb bud morphology ( J:211773 )

♂

IMPC - JAX

abnormal placenta size ( J:211773 )

IMPC - JAX

homeostasis/metabolism

edema ( J:211773 )

IMPC - JAX

limbs/digits/tail

abnormal limb bud morphology ( J:211773 )

♂

IMPC - JAX

liver/biliary system

pale liver ( J:211773 )

♂

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5630906

ht2

• Allelic Composition: Bloc1s2^{tm1.1(KOMP)Mbp}/Bloc1s2⁺
• Genetic Background: B6N(Cg)-Bloc1s2^{tm1.1(KOMP)Mbp}/J
• Cell Lines: DEPD00501_4_C09

Data Sources

IMPC Data for Bloc1s2

hematopoietic system

thrombocytopenia ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

decreased circulating free fatty acids level ( J:211773 )

♂

IMPC - JAX

increased circulating alanine transaminase level ( J:211773 )

♀

IMPC - JAX