All Phenotypes Spo11<tm2.1Rdco> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Spo11^tm2.1Rdco
targeted mutation 2.1, R Daniel Camerini-Otero
MGI:5490537

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Spo11^tm2.1Rdco/Spo11^tm2.1Rdco	B6.129S6-Spo11^tm2.1Rdco	MGI:5490539

Allelic Composition	Spo11^tm2.1Rdco/Spo11^tm2.1Rdco
Genetic Background	B6.129S6-Spo11^tm2.1Rdco

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spo11^tm2.1Rdco mutation (0 available); any Spo11 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal male meiosis ( J:194067 )

• male germ cells lack double strand breaks and are defective recombination and synapsis

• however, preleptotene pairing is normal

arrest of male meiosis ( J:194067 )

• in early prophase I

cellular

abnormal male meiosis ( J:194067 )

• male germ cells lack double strand breaks and are defective recombination and synapsis

• however, preleptotene pairing is normal

arrest of male meiosis ( J:194067 )

• in early prophase I

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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