Phenotypes associated with this allele

• Allele Symbol: Pax3^Sp-1Xzg
• Allele Name: splotch 1 Xizhi Guo
• Allele ID: MGI:5490564
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pax3^Sp-1Xzg/Pax3^Sp-1Xzg	C57BL/6J-Pax3^Sp-1Xzg	MGI:5490566
ht2	Pax3^Sp-1Xzg/Pax3^+	C57BL/6J-Pax3^Sp-1Xzg	MGI:5490565

Genotype
MGI:5490566

hm1

• Allelic Composition: Pax3^Sp-1Xzg/Pax3^Sp-1Xzg
• Genetic Background: C57BL/6J-Pax3^Sp-1Xzg

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:196566 )

• mice die around E13.5

embryo

open neural tube ( J:196566 )

spina bifida ( J:196566 )

limbs/digits/tail

abnormal limb morphology ( J:196566 )

nervous system

open neural tube ( J:196566 )

spina bifida ( J:196566 )

exencephaly ( J:196566 )

Genotype
MGI:5490565

ht2

• Allelic Composition: Pax3^Sp-1Xzg/Pax3⁺
• Genetic Background: C57BL/6J-Pax3^Sp-1Xzg

pigmentation

white spotting ( J:196566 )

• a symmetrical cluster of white coat on the midline of the abdomen, as well as at distal legs and tails

• occasional small white spots on the back

belly spot ( J:196566 )

hypopigmentation ( J:196566 )

decreased tail pigmentation ( J:196566 )

limbs/digits/tail

decreased tail pigmentation ( J:196566 )

curly tail ( J:196566 )

• occasional

integument

white spotting ( J:196566 )

• a symmetrical cluster of white coat on the midline of the abdomen, as well as at distal legs and tails

• occasional small white spots on the back

belly spot ( J:196566 )

decreased tail pigmentation ( J:196566 )