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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prg4tm1(GFP/cre/ERT2)Abl
targeted mutation 1, Andrew Lassar
MGI:5490969
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prg4tm1(GFP/cre/ERT2)Abl/Prg4tm1(GFP/cre/ERT2)Abl involves: 129 * C57BL/6J MGI:5490972


Genotype
MGI:5490972
hm1
Allelic
Composition		 Prg4tm1(GFP/cre/ERT2)Abl/Prg4tm1(GFP/cre/ERT2)Abl
Genetic
Background		 involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prg4tm1(GFP/cre/ERT2)Abl mutation (1 available); any Prg4 mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:197163 )
N
• homozygotes are viable and fertile

skeleton
decreased chondrocyte number ( J:197163 )
• homozygotes show a loss of the superficial-most layer of articular chondrocytes in joints
abnormal joint morphology ( J:197163 )
• homozygotes display synoviocyte hyperplasia in joints




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory