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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dp(5Gtf2i-Gtf2ird1)1Lro
duplication, Chr 5, L Osborne 1
MGI:5490970
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Dp(5Gtf2i-Gtf2ird1)1Lro/Dp(5Gtf2i-Gtf2ird1)1Lro involves: 129P2/OlaHsd * C57BL/6 * DBA/2 MGI:5490975
ht2
Dp(5Gtf2i-Gtf2ird1)1Lro/+ involves: 129P2/OlaHsd * C57BL/6 * DBA/2 MGI:5490977


Genotype
MGI:5490975
hm1
Allelic
Composition
Dp(5Gtf2i-Gtf2ird1)1Lro/Dp(5Gtf2i-Gtf2ird1)1Lro
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dp(5Gtf2i-Gtf2ird1)1Lro mutation (1 available); any Dp(5Gtf2i-Gtf2ird1)1Lro mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• more ultrasonic vocalizations than in wild-type mice or Gtf2iGt(YTA365)Byg heterozygotes during maternal separation period
• however, vocalizations decline over time of separation




Genotype
MGI:5490977
ht2
Allelic
Composition
Dp(5Gtf2i-Gtf2ird1)1Lro/+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dp(5Gtf2i-Gtf2ird1)1Lro mutation (1 available); any Dp(5Gtf2i-Gtf2ird1)1Lro mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• more ultrasonic vocalizations than in wild-type mice or Gtf2iGt(YTA365)Byg heterozygotes during maternal separation period
• however, vocalizations decline over time of separation





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory