All Phenotypes Prdm1<tm3.1Liz> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prdm1^tm3.1Liz
targeted mutation 3.1, Elizabeth K Bikoff
MGI:5491215

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prdm1^tm3.1Liz/Prdm1^tm3.1Liz	involves: 129S/SvEv	MGI:5491221

Allelic Composition	Prdm1^tm3.1Liz/Prdm1^tm3.1Liz
Genetic Background	involves: 129S/SvEv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm1^tm3.1Liz mutation (2 available); any Prdm1 mutation (66 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• mice die between E9.5 and E10.5

embryo

abnormal embryo development ( J:196531 )

• authors state that mice exhibit identical morphological disturbances as in Prdm1^tm1.1Clme homozygotes

embryonic growth retardation ( J:196531 )

• at E10.5

abnormal placenta morphology ( J:196531 )

• authors state that mice exhibit identical morphological disturbances as in Prdm1^tm1.1Clme homozygotes

growth/size/body

embryonic growth retardation ( J:196531 )

• at E10.5

hematopoietic system

hematopoietic system phenotype ( J:196531 )

N	• unlike Prdm1^tm1.1Liz homozygotes, mice exhibit normal plasma cell differentiation

immune system

immune system phenotype ( J:196531 )

N	• unlike Prdm1^tm1.1Liz homozygotes, mice exhibit normal plasma cell differentiation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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