All Phenotypes L1cam<tm4.1Vlem> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

L1cam^tm4.1Vlem
targeted mutation 4.1, Vance Lemmon
MGI:5491826

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	L1cam^tm4.1Vlem/Y	either: 129S4.129S2-L1cam^tm4.1Vlem or B6.129S4-L1cam^tm4.1Vlem	MGI:5491872

Allelic Composition	L1cam^tm4.1Vlem/Y
Genetic Background	either: 129S4.129S2-L1cam^tm4.1Vlem or B6.129S4-L1cam^tm4.1Vlem

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
L1cam^tm4.1Vlem mutation (0 available); any L1cam mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:197240 )

N	• mice exhibit normal survival

behavior/neurological

behavior/neurological phenotype ( J:197240 )

N	• mice exhibit normal spatial memory

impaired coordination ( J:197240 )

• on an accelerating rotarod

• however, mice are able to remain on an immobile rod without falling

nervous system

nervous system phenotype ( J:197240 )

N	• mice do not exhibit hydrocephalus and unmyelinated and myelinated axons

abnormal neurite morphology ( J:197240 )

• reduced number of branches and neurite total or longest neurite lengths when cultured on L1-Fc substrate

• reduced number of branches when cultured on laminin substrate

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24