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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1(Cdkn1c)Jfpa
targeted mutation 1, James Padbury
MGI:5492378
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(Cdkn1c)Jfpa/Gt(ROSA)26Sor+
Myl2tm1(cre)Krc/Myl2+ 		involves: 129S7/SvEvBrd * C57BL/6 MGI:5492393


Genotype
MGI:5492393
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(Cdkn1c)Jfpa/Gt(ROSA)26Sor+
Myl2tm1(cre)Krc/Myl2+
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Cdkn1c)Jfpa mutation (1 available); any Gt(ROSA)26Sor mutation (993 available)
Myl2tm1(cre)Krc mutation (2 available); any Myl2 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
increased coronary flow rate ( J:197451 )
• higher coronary flow after ischemia/reperfusion injury
abnormal heart left ventricle pressure ( J:197451 )
• significantly better cardiac function after 30 minutes of ischemia followed by 30 minutes of reperfusion than in controls
• higher left ventricle developed pressure than in controls
• higher rate pressure product

homeostasis/metabolism




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory