Phenotypes associated with this allele

• Allele Symbol: Mdk^{tm1.1(KOMP)Mbp}
• Allele Name: targeted mutation 1.1, Mouse Biology Program, UC Davis
• Allele ID: MGI:5493326
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mdk^tm1.1(KOMP)Mbp/Mdk^tm1.1(KOMP)Mbp	C57BL/6N-Mdk^tm1.1(KOMP)Mbp/J	MGI:5639396
ht2	Mdk^tm1.1(KOMP)Mbp/Mdk^+	C57BL/6N-Mdk^tm1.1(KOMP)Mbp/J	MGI:5631300

Genotype
MGI:5639396

hm1

• Allelic Composition: Mdk^{tm1.1(KOMP)Mbp}/Mdk^{tm1.1(KOMP)Mbp}
• Genetic Background: C57BL/6N-Mdk^{tm1.1(KOMP)Mbp}/J
• Cell Lines: DEPD00513_1_C09

Data Sources

IMPC Data for Mdk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired righting response ( J:211773 )

IMPC - JAX

hematopoietic system

decreased mean corpuscular volume ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

increased circulating cholesterol level ( J:211773 )

♂

IMPC - JAX

increased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - JAX

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5631300

ht2

• Allelic Composition: Mdk^{tm1.1(KOMP)Mbp}/Mdk⁺
• Genetic Background: C57BL/6N-Mdk^{tm1.1(KOMP)Mbp}/J
• Cell Lines: DEPD00513_1_C09

Data Sources

IMPC Data for Mdk

homeostasis/metabolism

increased circulating sodium level ( J:211773 )

♂

IMPC - JAX

increased circulating chloride level ( J:211773 )

♂

IMPC - JAX